Combinatorial therapy for triple negative breast cancer using hyperstar polymer-based nanoparticles.
نویسندگان
چکیده
We report the ability of a novel combinatorial therapy obtained from nanoparticles of hyperstar polymers encompassing drugs to selectively target triple negative breast cancer (TNBC) cell proliferation through STAT3 and topoisomerase-II pathways. This nano-cocktail was at least two to four fold better than the individual drugs and 6-20 times more selective than the parent drugs.
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عنوان ژورنال:
- Chemical communications
دوره 51 93 شماره
صفحات -
تاریخ انتشار 2015